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In the published study many novel σ32 binding sites were described.
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In the present study, the localization of these binding sites is described for the first time.
The design and synthesis of coordinative supramolecular polygons with open binding sites is described.
The syntheses of tris 2-nicotinic acid)metris 2-nicotinicher 5 acidtris(2-picolinic acid)methanol methyl ether 6, two tridentate ligands designed to also act as scaffolds for constructing chiral environments around their metal binding sites, is described.
These binding sites are described and discussed in Supplementary Information.
The advantages and limitations of ProBiS in the detection of protein protein, protein small ligand and protein DNA binding sites are described using a quantitative performance evaluation on a test set of 39 proteins.
The design, synthesis, and use of lerisetron-based molecular probes to investigate the 5-HT3R binding site are described.
In Bcl-xL, the chelerythrine binding site is described as being located in the BH groove of helix α4, α5 and α6, which is composed of residues F131, R132, V135, Y173 and H177 (Figure 3C) [3C].
A binding site is described by any amino acid for which at least one heavy atom is closer than 4.5 Å from any heavy atom of the bound pharmacological ligand.
The phosphorylation of a binding site is often described in a different layer than the layer in which effector binding to the phosphorylated binding site is described.
This binding site was described by the authors on the β-lg dimer interface, binding 2 mol of palmitate per dimer of β-lg with an affinity constant in the order of 10 M−10
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