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Residues defining the binding sites were selected for site-directed mutagenesis.
Potential binding sites were elucidated by docking.
Third, transcription factor binding sites are enriched amongst the top association results pointing towards disturbed regulatory network function in asthma.The next wave of asthma genetic studies will use full-genome sequencing and overcome most GWAS-associated problems.
Twelve binding sites are present within the dodecameric channel.
[3H]nicotine binding sites are associated with mammalian optic nerve terminals.
These binding sites are highly charged.
Noteworthy, these binding sites are juxtaposed to GATA3-binding sites.
For example the p53 binding site was enriched amongst genes dysregulated by five compounds (K, L, N, P, and Q).
There are 10 ATP-binding sites and one active site residue of which 8 ATP-binding sites are reported amongst somatic mutations responsible for lung cancer.
The left TALEN binding site is 5-TACAACAATCTCCAGAT-3 and the right TALEN binding site is 5-ATGCCACAGACGAAGGGCCCATA-3.
Thus, the underlying Ca2+ binding site is not intracellular.
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