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To use the entropy-based discretization, each track of data was sorted, and a list of known or predicted binding sites was mapped to the probe coordinate and used as the class label c of each data point.
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The TF binding sites are mapped onto the mm8 (February 2006) mouse assembly.
Transcription factor binding sites were mapped within hotspots using the P-Match program available from TRANSFAC [52].
The nucleotide modifications (by DMS), the pauses corresponding to nuclease (TI and VI) cleavage sites and the toe prints corresponding to PTB binding sites were mapped to MFOLD predicted structure for clarity (Fig. 3).
Using synthetic α-actinin-4 peptides, HAMLET binding sites were mapped to the N-terminal actin-binding domain and the proposed β integrin-binding central rod domain between spectrin repeats 1 and 2, suggesting that HAMLET might impair these essential interactions, [5], [6], [10].
Ribosome binding sites were mapped when possible according to the sequence described in reference [ 41].
Sox2 stable binding sites were mapped by low-excitation 2D single molecule imaging condition (Video 7 ).
In the first step, putative TF binding sites were mapped in the DNA sequence of enhancers and controls.
TRANSFAC's 522 mammalian minimum false positive matrix profiles of binding sites were mapped to the promoter regions (see Methods).
AR binding sites were mapped to transcriptional start sites (TSS) of genes based on refFlat (hg19) table from UCSC Genome Browser.
Interestingly, binding sites are mapped only in the intergenic regions (between rpmH– dnaA, dnaA– dnaN, yqeG– sda, ywlB– ywlC, jag– thdF, yycS– yydA, ywcI– vpr, and gcp– ydiF).
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