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A trend towards enrichment of GATA3 binding sites was found for MBOAT7 (P = 0.12).
Hence, the physiological concentration range for TBP binding sites was found to be 10-5M to 10-9M.
Differential AR binding sites were clearly enriched for specific chromosomes, and a strong enrichment of resistance-associated AR binding sites was found at chromosome 8.
For the six best genes of the ErbB2+ over-expressing cluster, a common framework consisting of NF-κB and ETS1 transcription factor binding sites was found.
In an attempt to identify TFs that could cooperate with TFAP2A, a statistically significant enrichment for SP1 binding sites was found for TFAP2A-activated but not repressed genes.
No statistically significant enrichment for transcription factor binding sites was found due to the wide representation of cellular functions in this dataset.
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(B) A conserved SigB binding sites were found from 29 TSSs (p-value of 1.51 × 10−8).
All these binding sites were found within regulatory regions including upstream of promoters, promoters, and 5′-proximal to coding regions (Supplementary Table 1).
Many binding sites were found to shift dramatically between embryos and starved larvae, from developmentally regulated genes to genes involved in metabolism.
Ligand-binding sites are usually found in deep protein surface cavities, but it should be emphasized that not all binding sites are found in deep cavities.
Between one and six Tra2-ISS binding sites were found in intron is1 in all species (Fig. 5).
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