Sentence examples for binding sites that show from inspiring English sources

Figure 5b highlights two distinct prothrombin potential binding sites that show a degree of structural similarity to each other.

Considered in Targetscan, the 15 nucleotides after the stop codon in a 3' UTR form poor microRNA target binding sites that show little ability to repress expression.

To search for potential p63 co-regulators during specific stages of epidermal stratification, we determined motif enrichment in the seven clusters of p63 binding sites that show differential H3K27ac occupancy patterns during differentiation.

Although it is important to capture each class of evidence for each TF and gene regulatory region, we offer only those binding sites that show strong evolutionarily conservation in the CBS website to avoid excessive exposition of information.

Moreover, when time-resolved binding of the TF factor was measured in a study, we restricted our attention further to only those ChIP-seq binding sites that show circadian (cycling) binding of the TF.

This was confirmed by chromatin IP and site-directed mutagenesis of the Pax2 and Sox2 binding sites that showed that Pax2 and Sox2 TF are bound directly to the enhancer and regulate GFP expression in vivo.

Furthermore, we tested CTCF binding at the same regions by ChIP-qPCR, and observed a reduction in binding upon Oct4 KD wherever chromatin accessibility decreased, whereas control CTCF binding sites that showed no difference in accessibility upon Oct4 KD showed no decrease in CTCF binding.

We observe ping-pong kinetics consistent with one substrate/inhibitor binding site that shows selectivity for the oxidation state of the FAD cofactor, suggesting that selective inhibition of the liver versus red blood cell forms of malaria may be possible.

There is indirect activation of hemA expression (Additional file 2: Table S2) with possible direct activation of ferrochelatase (hemH) expression with a predicted FnrL binding site that shows good similarity to the FnrL consensus recognition sequence.

Similar to the promoter of human CDKN1A/P21, the murine Cdkn1a/p21 promoter also contains Ap4-binding sites that showed occupancy by Ap4 (Fig. 4d).

Indeed, the transposable elements contain transcription factor binding sites that have been shown to mediate PRL transcription in human uterine decidualised endometrial cells and lymphocytes.