Sentence examples for binding sites that occur from inspiring English sources

The majority of RNA-binding proteins, including splicing regulators, tend to have short, degenerate binding sites that occur frequently throughout the genome.

In addition, the transcription factor binding sites that occur within 5 kb upstream of the miRNA gene start site have been analysed using the UCSC Genome Browser tool (http://genome.ucsc.edu).ucsc.edu

Genes robustly expressed in glycogen trophoblast cells (Prl6a1, Prl2a1, Prl7b1, Prl7c1, Prl8a9) were analyzed for modules of transcription factor binding sites that occur in all five promoter regions.

On the other hand, the overwhelmingly large number of cryptic (i.e. false positive) binding sites that occur throughout the eukaryotic genome tend to be masked and inaccessibly wrapped in nucleosome particles, which are themselves stacked into a higher-order, dense chromatin configuration.

In contrast, HPPH-Gal binding to the cell surface was limited by saturation of extracellular binding sites that occurred at ∼1000 nℳ HPPH-Gal (Supplementary Figure 1E).

This indicated that NFI binding sequences are not significantly enriched at mouse promoters as compared to intergenic and transcribed regions, but that it is the association to the binding sites per se that occurs preferentially at promoters.

Most of these methods utilize some type of statistical background-modeling approach to identify putative transcription factor binding sites as sequence motifs that occur in the promoter regions of co-expressed genes in greater frequency than would be expected if a random set of promoter regions were considered (i.e. the background).

Extending the word neighbourhood to the reverse complement (N2 rc ) improves the performance, showing that binding sites can occur on both strands of the CRM.

Another contribution is nonspecific binding - referring to any nonsaturable binding that occurs to other sites than Aβ (for example, to membranes or lipid fractions).

We use UCSC annotations (cf. Methods) and find that high stringency hERα binding sites (t>16) occur both in intergenic regions (~56%) and along genes (~44%) (Table 1).

We use coding regions as control sequence because it is less likely that functional SphR binding sites would occur in coding regions (for details see Methods).