Sentence examples for binding sites that may from inspiring English sources
Comparative sequence analysis indicated that many of these newly identified sites are highly conserved across five sequenced sensu stricto yeast species and, therefore, are probably functional in vivo binding sites that may be used in a condition-specific manner.
Our data strongly support the notion that tRNA gene transcription in eukaryotes is modulated by composite TFIIIB binding sites that may confer responsiveness to variation in TFIIIB activity and/or concentration.
These sequences are putative SP1 transcription factor binding sites that may represent important cis-acting DNA regulatory elements that govern the expression of Cox-2.
RAVEN combines phylogenetic footprinting with scanning of all sequence variants for transcription factor binding sites that may be differentially affected by the variation.
To identify potential transcription factor binding sites that may be influenced by genetic variation at the Lp(a) locus, we scanned the genomic sequences surrounding the 24 Lp(a) associated SNPs using Jaspar (http://www.jaspar.genereg.net) and Transfac (http://www.gene-regulation.com) positional weight matrices (PWMs) with quantitative thresholds for match quality (see Methods).
For example, the CXCL8 promoter contains AP1 transcription factor binding sites that may co-regulate expression of the cytokine [ 44].
This study presents evidence for a possible non-cholinergic binding site that may play a role in the mechanism of immunomodulation by nicotine.
These enzymes may employ two means to promote protonation of the alkoxide intermediate: a potential proton donor or hydrogen-bonding group within the active site (His271 in PLR; Ser263 and Ser267 in PCBER), and a more open binding site that may allow access to the intermediate by bulk water.
4th paragraph "Thus, our analysis suggests the loss of a binding site that may be the result of a loss of expression of the transcription factor that binds".
