Sentence examples for binding sites that control from inspiring English sources

Previous experiments identified functional SOX9 binding sites that control the activity of chondrocyte-specific transcriptional enhancers in the Col2a1, Col11a2 [10], Aggrecan [12] and Cdrap [11] genes.

As Gal4 reporter construct was used the pMN-Luc plasmid containing a thymidine kinase promoter with five tandem repeats of the yeast GAL4 binding sites that control expression of the firefly luciferase gene.

Careful bioinformatic and experimental analysis of promoters of ORs expressed in other tissues could reveal recently arisen transcription factor binding sites that allow novel regulatory control in non-olfactory tissues.

The regulatory components of cyclic nucleotide-dependent protein kinases each harbor two tandem cyclic nucleotide binding sites that allow allosteric and cooperative control of kinase activity.

Interestingly, experiments conducted on transcriptional termination factors in D. melanogaster have identified the positions of some binding sites that are responsible for the control of multiple transcription units on the mtDNA of this species [ 40].

We found during bicalutamide treatment that HES6 was able to maintain many AR binding sites that were lost in the EV control cells.

Furthermore, we tested CTCF binding at the same regions by ChIP-qPCR, and observed a reduction in binding upon Oct4 KD wherever chromatin accessibility decreased, whereas control CTCF binding sites that showed no difference in accessibility upon Oct4 KD showed no decrease in CTCF binding.

To investigate whether PAX3-FKHR controls CPT1A transcription by binding to CPT1A's promoter, we analyzed the DNA sequence 5′ to the CPT1A transcription start site and identified 3 putative PAX3-FKHR binding sites that matched the consensus composite sequence: a paired-box domain (PD) binding site (GTTC/AT/C) followed by a linker sequence and a homeodomain (HD) binding site (ATTA).

Indeed, control of HLA-C surface expression has been correlated with the presence of a microRNA binding site that affects HLA-C expression and the control of HIV disease [ 61].

In bacteria, IEPs are encoded entirely within loops of their host group II introns, and possess regulatory features such as promoters and ribosome-binding sites that are distinct from those that control expression of the host gene in which the intron resides [ 39].

A large positive wi indicates a binding site that is strongly associated with the enhancers, whereas negative weights correspond to the binding sites associated with the control set.