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Two of the mRNAs, including the ATPase subunit 6 and ND7-550 (5' end of NADH dehydrogenase subunit 7) that have open, accessible anchor binding sites show very efficient gRNA targeting.
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Instead, we found the shorter-lived Sox2 binding sites showed very little clustering and greatly reduced fluctuation amplitudes of the pair correlation function curves.
However, the sequence logo and known FruR binding sites show that the outermost motif positions are very poorly conserved, providing little information above that of background 'noise'noise
A comparison of the CoA bound binding sites with the statin bound binding sites showed rearrangements.
The data of number of binding sites showed uniformity.
In the upregulation set, Foxd3 binding sites showed the strongest signal after Oct1 sites (Table S4).
The mutation of individual binding sites showed no effect on PTB binding (data not shown, Fig 4a and b).
(C) View of the i1 binding site showing the inhibitor overlapping with helix a10 of CNOT7.
This binding site showed a lower level of conservation than miR-1279 and miR-548j binding sites.
Oligonucleotides corresponding to this putative NF-κB-binding site showed binding to NF-κB.
Somewhat less favourable than the energies of association calculated for all the monomeric decoron to collagen receptor models, which range from –45 to –175 kJ/mol (with the exception of the non-binding site, negative control models, which show very small or positive energies of association).
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