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The sulfatase genes potentially could encode for enzymes that modify gycosaminoglycans to generate binding sites required for attachment of B. pilosicoli [46].
In contrast, pretreatment of blood with M1234 annexin A5 mutant (lacking the four Ca2+ binding sites required for interaction with PS) had no effect on fibrin formation or the distribution of OG488-fibrinogen on the thrombus surface (Fig. 5).
In order to extract the actual binding sites required for CMRegNet, we performed the following strategy.
This activity would normally destroy the binding sites required for adhesion to host tissue.
The value of m is a cut-off that represents the number of publications or binding sites required for S〈 p,bs〉 to obtaining their maximum values.
To examine the minimal number of λCl repressor binding sites required for effective repression, a single λCl operator site and dual λCl operator sites of perfect dyad symmetry were fused downstream of the pBAD promoter, before the RFP gene [ 40].
Similar(53)
The cNef region falls in the "central conserved region" and includes the second alpha helix (key for interaction with the src kinase SH3) and the three adjacent beta strands that compose the central structured core domain [29], and thus contains a key binding site required for many cellular effects of Nef, and sequences that are a crucial structural scaffold.
The kinase module in the yeast complex was found to block a binding site required for RNAPII.
The last identified motif present in this Cab promoter is a GATA-containing element similar to an activation sequence binding site required for leaf-specificity in transgenic tobacco, but not light regulation [ 19].
This suggests that the CD44 variant has an intermediate affinity for the ligand-binding site required for cell rolling.
Thus, the size of the ssDNA-binding site required for second SSB binding is likely to be dependent on the C-terminal domain of SSB.
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