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In addition, it might show that WFA binding, indicating the presence of highly charged anionic binding sites, provides a signature for the neuroprotective properties of PNs.
Turnover of transcription factor binding sites provides a simple model whereby the function of distantly related promoters can be conserved while their sequences diverge (Hancock et al. 1999; Ludwig et al. 2000; Dermitzakis and Clark 2002).
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Various miRNA binding sites provide a number of choices which not only meet different needs under various processes but also avoid unwanted cross-reactions.
It is suggested here that the Tra2-ISS binding sites provide a discriminative feature for the tra and dsx pre-mRNAs regions involved in sex-specific splicing regulation.
Identification of the SH3 binding site provides a basis for understanding the interaction between the SH3 domains and their targets.
This binding site provides a mechanism for the incorporation of urokinase into the cell membrane.
Consequently, the composite LysM1 LysM3 binding site provides a single binding event with ultra-high (pM) affinity for chitin binding, the highest chitin-binding affinity described in nature, which is extremely competent to sequester chitin oligosaccharides.
Although PglB is a prokaryotic homologue that modifies a slightly different consensus sequence, its peptide binding site provides a structural basis for the mammalian OST co- and post-translational N-glycosylation kinetics of the different NXS consensus sites.
The structure of the p300/acetonyl-CoA and p300/CoA complexes with two PEG moieties bound proximal to the cofactor binding site provides a more rational approach to developing potent and selective small molecule p300 inhibitors.
This difference is attributable to powerful protein-binding sites for NADH; the redox buffer capacity of these titratable NADH-binding sites provides a cytosolic set point at about 1 μ M free NADH, despite much higher total cytosolic NADH (pNADH=6).
The analysis of transcription factor binding sites provided an insight into transcript level data.
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