Sentence examples for binding sites playing an from inspiring English sources

Indeed, alternative splicing could produce different isoforms which may or may not contain functional binding sites, playing an important role in modulating the interaction between miRNA and target.

Many transcription factor binding sites are highly conserved throughout the sequences and the discovery of the location of such binding sites plays an important role in understanding gene interaction and gene regulation.

Specificity and differential binding affinity of HU/IHF proteins towards their target binding sites play a crucial role in their regulatory dynamics.

It remains unclear whether a subset of CTCF binding sites plays a functional role in establishing/maintaining chromatin topological domains.

These findings that the presence of a water molecule in the hydrophobic binding site plays an important role are a step towards a quantitative understanding of the character of bridge water in enzyme-inhibitor binding.

We found that Sp1 binding sites are important both for basal and hyperosmolarity-induced promoter activities, whereas the NF-κB binding site plays an important role in the hyperosmolarity-induced promoter activity.

Since proteins carry out their functions through interactions with other molecules, accurately identifying the protein-ligand binding site plays an important role in protein functional annotation and rational drug discovery.

In addition, luciferase and ChIP assays showed that the Sp1-binding sites played an important role in regulating the promoter activity of the GLS gene and mithramycin exactly behaved as an Sp1 inhibitor.

The target protein and the characteristics of its binding site play a major role.

We asked whether methylation of the potential c-Myc binding site plays a role in the regulation of MYCT1.

We conclude that the CUX1 consensus binding site plays a role in the recruitment of CUX1 at specific genomic locations, but the presence of a consensus site is not sufficient.