Sentence examples for binding sites overlapping with from inspiring English sources

Here, we propose a scheme that allows performing large-scale screening of all protein complexes and finding putative small-molecule and/or peptide binding sites overlapping with protein protein binding sites (so-called "multibinding sites").

Whereas we cannot exclude the possibility that we could not detect binding of CPEB to Eph/ephrin CPEs for technical reasons, it might also be that either CPEB is not an interactor of these CPEs or it was outcompeted by other proteins that interacted with the AREs or HuR binding sites overlapping with or located in close proximity to the CPEs.

TFs, modified histones and DNase with binding sites overlapping with H2H blocks were identified and annotated with H2H pairs for further analysis.

In addition, all five HSF binding sites overlap with binding sites identified in Kc167 cells for the ecdysone receptor complex (EcR-C) [51], the nuclear receptor complex responsible for the stage and tissue specific activation of Eip75B, Eip74EF, and br [52], [53].

Consistent with this, we found that the median enrichment level of Sty1 at the binding sites overlapped with the major Atf1/Pcr1 binding sites was higher than that of the Sty1 at the binding sites non-overlapped with the Atf1/Pcr1 binding sites (4-fold versus 2.3-fold higher than the array median; p-value = 3.03e-08) (Figure 6D).

In contrast, only 43% of RARα binding sites overlapped with those of RXRα.

For all promoters the specific region containing the transcription factor binding sites overlap with a region that is DNaseI sensitive.

When 50% of the nucleotides in the binding sites overlapped with the genomic annotations, they were correspondingly annotated.

In ChIP-chip assays in Drosophila S2 cells, it was observed that 20% of TLF binding sites overlap with TBP binding sites [ 83].

Furthermore, and also consistent with what has been reported for mouse adipocytes [ 16], a high percentage (49.5%) of the PPARγ binding sites overlap with C/EBPα binding sites.

Interestingly, 68% of the 15,740 newly identified RING1B binding sites overlapped with CGIs, and 77% of these were coupled to transcription start sites.