Sentence examples for binding sites of this from inspiring English sources

In the first studies of MeCP2, abundant binding sites of this protein were found in genomic chromatin, and MeCP2 seemed capable of long-range repression [17].

There were no previously known polymorphisms in the primer binding sites of this amplicon that could otherwise interfere with faithful allele amplification.

We then decided to reassess the effect of CyaY in the new assay conditions given that the binding sites of this protein and Fdx overlap [16,18,19].

For example c-MYC, since it has been observed that the binding sites of this TF are highly present in osteogenic genes and differentiation to osteoblast occurs under the over-expression of c-MYC [ 55].

As CCR5 also shares 74% identity with the receptor CCR2, it is perhaps unsurprising that the molecule also has excellent potency and efficacy at the latter receptor and, via a programme of ab initio receptor modelling and site-directed mutagenesis, we have been able to compare the binding sites of this molecule in both CCR2 and CCR5 (Hall et al., 2009).

In this study, we developed a new method for predicting the structure of H3 loops of immunoglobulins, a rather elusive and complex problem that is however essential for obtaining an accurate view of the antigen binding sites of this important class of molecules.

Indeed, at least one member of the CRP/FNR superfamily is encoded in these 13 genomes, and it has been shown that the binding sites of the members of this TF superfamily are well conserved across many species with a wide range of evolutionary distance [ 40].

This structure reveals the chemical environment or ' pharmacophore' presented by the ligand binding site of this Aβ segment, that is, orange G binds to stacked β-sheets of Aβ.

To our knowledge, this is the first molecular modelling study conducted with the catalytic binding site of this crystal structure.

The binding site of this enzyme possesses two main subpockets: the catalytic anion-binding site and the hydrophobic specificity pocket.

If the query chain has no satisfactory homologous bound template, the binding site of this query chain will be detected as the following procedure.