The involvement of surface-displayed MHC class I molecules in graft rejection and the mitigation of transplant immunogenicity through interference with MHC class I protein recognition have been well documented.
There is also support for this observation in a very recent study by Boulware et al. [24], where cell libraries of surface-displayed random peptides were incubated with exogenous TEVp and screened for TEVp substrates.
For industrial bioconversion processes, the utilization of surface-displayed lipase in the form of whole-cell biocatalysts is more advantageous, because the enzymes are displayed on the cell surface spontaneously, regarded as immobilized enzymes.
For industrial bioconversion processes, the utilization of surface-displayed lipase in the form of whole-cell biocatalysts is more advantageous, because the enzymes are displayed on the cell surface spontaneously, regarded as immobilized enzyme, and can be separated easily.
The third category, the creation of surface-displayed cellulosomes, requires native secretion or fusion mechanisms as well, however heterologous systems, such as Ruminococcus flavefaciens [ 69] and Streptococcus pyogenes [ 72], have also been utilized.
Previously, we have found the novel binding sites of 15d-PGJ2 on the cell surface [4].
In this study, the binding sites of hHAsα2,6 and hHAsα2, 6* were successfully displayed on yeast cell surface (Fig. 1b).
The coregulator binding surface is a region where the binding sites of corepressor and the coactivator overlap.
Predicted ligand binding sites of YD1.
≡SZn denotes the surface binding site of ZnS.
