Sentence examples for binding sites of other from inspiring English sources

The first reports on STAT6-mediated inhibition showed that the repressor function of STAT6 exerts its effect by occupying overlapping binding sites of other transcription factors, thereby sterically hindering their ability to bind and thus activate their target genes 22, 23.

These observations bolster previous reports on binding sites of other TFs within repeats.

Moreover, the known binding sites of other PBP proteins are always located at the interface between the two domains as seen in the CA3427 structure.

We note the ZNF274 motifs do not have high similarity to binding sites of other factors, but we did identify several quite long motifs.

In distinction to previous reports on binding sites of other transcription factors within repeats [18], [19], [20], [21], we demonstrate a specific induction of STAT1 binding to selected repetitive sequence elements in reaction to a signal increasing the nuclear concentration of STAT1.

It is possible that some of the CNRs lie within true binding sites of other proteins that were not identified in this study.

The domain V of 23S rRNA is the binding site of other translation inhibitors like chloramphenicol, florfenicol and quinupristin-dalfopristin, and the G2576T mutation was shown to confer cross-resistance to these antibiotics.

We showed in the first series of computations (Fig. 2A) that ATP-binding sites of protein kinases do not resemble neither ATP-binding sites of other kinases nor other ATP-binding cavities [41], [70].

Engineering AChBPs with the ligand-binding sites of specific nAChR subtypes, or with the ligand-binding sites of other ligand-gated ion channels, is expected to identify specific pairwise interactions underlying nAChR selectivity and further expand the potential of this protein scaffold to discover novel pharmacological probes.

The interactions between thermorubin and the ribosome, as well as its adjacency to the observed binding sites of three other antibiotic classes, may enable the design of novel derivatives that share thermorubin's mode of action but possess improved pharmacodynamic properties.

Our finding suggests the possibility that the binding sites of the other TFs may partially overlap with that of DAF-16.