Sentence examples for binding sites of many from inspiring English sources

In addition, the binding sites of many TFs are so similar that they do not allow a reliable prediction of function; clearly, sequence preferences can be altered by the binding context [23].

MacIsaac et al. used evolutionarily conservative criteria to computationally identify the binding sites of many TFs.

The in vitro binding sites of many AP2/ERF superfamily proteins have been studied in detail.

The ambiguity in binding sites of many of the probes (Table 2 and Figure 7) prohibits detailed interpretation.

The drawback of open chromatin assays is their lack of specificity, as the identified sites typically correlate with the binding sites of many different transcription factors 32.

In the TFCONES database, a considerable fraction of conserved elements were annotated overlapping with the binding sites of many transcription factors [ 28].

Association studies of affected individuals with Cystic Fibrosis identified the causal variant, a regulatory SNP rs7910656 on the non-coding region of FAS gene on human chromosome 10q24.1, which includes the binding site of many transcription factors especially the NFκB complex, but no molecular alterations were detected by conventional approaches.

However, the C at position −12 has been replaced with A or T in RpoN-binding sites of many pspA homologs.

Initially, a search using the motif GTTA-5 N-TAAC, conserved in Zur-binding sites of many proteobacteria was carried out.

This was perhaps best observed with STI-571 (Gleevec, imatinib mesylate, Novartis Pharma, Basel, Switzerland), a competitive inhibitor of the ATP-binding site of many kinases (Klejman et al, 2002).

We collected 115 known binding sites of RBPs including many well-characterized splicing factors from the literature (Ule et al., 2003; Anderson et al., 2012; Dittmar et al., 2012; Ray et al., 2013; Vanharanta et al., 2014).