Sentence examples for binding sites of certain from inspiring English sources

These intronic DMRs were significantly enriched for diverse regulatory elements, such as enhancers and binding sites of certain transcriptional factors (e.g., Pol3).

To test for such repressions we analyzed in each cell line the 3′ UTRs of the 5% of genes with the lowest translational efficiency for a significant over-representation of binding sites of certain miRNA families.

Not only do these represent the first inhibitors uniquely targeting the substrate binding site of EZH2 but also confirm our original hypothesis that the histone-binding sites of certain HKMTs are similar [ 33], and it is therefore possible to discover dual inhibitors targeting this supposedly divergent pocket.

If binding sites of a certain TF were frequently found in the off-target set of a candidate site, the binding motif of this TF will be searched as reported in the JASPAR database (http://jaspardev.genereg.net/) [ 23].

Several have indeed been demonstrated to possess enhancer function (reviewed in [50]) and an enrichment of sequence patterns characteristic of binding sites for certain developmental transcription factors has been found in a large subset of HCNEs [51].

Leaky expression of viral genes from replication-deficient viral vectors, however, is known to occur due to the presence of binding sites for certain cellular transcription factors in adenoviral promoters [ 43].

TESS (Transcription Element Search System) database software allowed assessing of potential binding sites for certain transcription factors in the candidate sequence.

The PPII-structured oligoPro elements are known to provide the binding sites for certain htt-binding proteins, some of which can bind to fibrils.

One important aspect of this role, crucial to understanding gene regulation [ 46], is the location of the preferred binding sites for certain proteins (transcription factor binding sites or TFBSs).

Although the binding sites of the same TF usually have a certain conservative feature and the same length, they can show some level of degeneration, and be located in very long non-coding sequences, making their computational prediction very difficult [ 9].

Remarkably, target sites containing certain transcriptional factor motif have enriched binding sites of relevant transcriptional factor in their off-target sets.