Sentence examples for binding sites may function from inspiring English sources

Exact(1)

Interestingly, the enriched TF binding sites may function as clock genes, controlling circadian rhythm [ 37].

Similar(59)

In a similar but reversed case, the REST gene, which itself contains a REST-binding site, may function to reduce its own expression so that differentiation can proceed unidirectionally.

These binding sites may reflect several additional functions for HLH-1, including its interactions with one or more co-factors to activate (or repress) gene expression or a role in chromatin organization distinct from direct transcriptional regulation of target genes.

If the accumulation of binding sites follows neutral trends, then most binding sites may actually be neutral to function, and therefore encode very little 'meaningful' information in terms of understanding the transcriptome.

Indeed, we find that accessibility over CTCF binding sites was reduced upon KD of the H3.3 deposition factor, Hira, suggesting that H3.3 incorporation within nucleosomes surrounding CTCF binding sites may be important for CTCF binding and/or function.

Similar binding sites often imply similar protein-protein interactions and similar functions; however, similar binding sites may also constitute traps for nonfunctional associations.

Unoccupied 'perfect' STAT1 binding sites may include cell type specific binding sites and suggest a required but not sufficient function of the nucleotide sequence for DNA-protein binding.

However, since this new function may not be essential for the species, the acquired hydrophobic binding sites may disappear in the evolutionary process.

Therefore, true binding sites may have SNPs less frequently than the non-binding sites.

These data suggest that additional binding sites may exist.

Not all binding sites may evolve under the same constraints.

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