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Therefore, SFN-mediated demethylation of CpGs of the CTCF binding sites may facilitate the binding of CTCF to the hTERT gene regulatory region to allow for CTCF-mediated down-regulation of hTERT expression in MCF-7 and MDA-MB-231 cells.
Atomic level details of these binding sites may facilitate future discovery of potential drugs.
These secondary binding sites may facilitate recognition by the THAP (Thanatos-associated protein) domain of the Galileo transposase.
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The structural divergences surrounding splice sites may facilitate the removal of the introns by spliceosome.
Consideration of binding competitiveness of a drug candidate against natural ligands and other drugs that bind to the same receptor site may facilitate the rational development of a candidate into a potent drug.
Choice of accelerometer wear-site may facilitate greater compliance in research studies.
Therefore, true binding sites may have SNPs less frequently than the non-binding sites.
Not all binding sites may evolve under the same constraints.
These data suggest that additional binding sites may exist.
miRNA binding sites may correspond to 3 open reading frames.
Since no presumptions about localization of binding sites prior to comparison are used, ProBiS may detect new binding sites and suggest ligands that these binding sites may accommodate.
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CEO of Professional Science Editing for Scientists @ prosciediting.com