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Ironically, there are NF-κB binding sites located within the HIV LTR [ 14] that can bind NF-κB and enhance HIV replication.
A purine-rich consensus motif was identified in binding sites located within exon sequences but not introns.
Particularly, we created a histogram by counting the number of AGO2 binding sites located within 600 kb upstream and downstream of L1 using the 25-kb interval size (Fig. 6C and 6D). Figure 6C and Figure 6D demonstrate the frequency distribution of AGO2 binding sites with respect to antisense L1 and sense L1, respectively.
This promoter function assay is the initial exploration of the roles for σ binding sites located within intragenic regions.
There are also 39 CgrA binding sites located within a protein coding sequence that have a gene located immediately downstream of the binding site (Fig. 3D).
Figure 4 reports the possible interactions between miR-93 and miR-93 binding sites located within the 3′UTR sequence of VEGF mRNA and IL-8 mRNA.
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This is important to exclude the possibility that the expression of our proof of concept, ppc, is controlled by a regulator which can bind on an unknown transcription factor binding site located within the used artificial promoters or the flanking regions in the genome.
A regulatory Ca2+ binding site located within the membrane adjacent to this hydrophobic cleft is responsible for activation by yet unknown mechanisms.
Figure 3 shows an example of a GlnR-dependent binding site located within the glnII promoter region.
Furthermore, BACE1-AS masks the miR-485-5p miR-485-5p miR-485-5pwithin the CDS of bindingRNA, and thereby counteractsiteR-485-5p-mediated repression of BACE1 mRNA translocated[ 60].
The second FnrL binding site located within the ccoN gene may be used for regulation of downstream cytochrome biogenesis proteins ccoGHIS since FnrL represses this second downstream operon.
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