Sentence examples for binding sites joined to from inspiring English sources

The CaSR gene encodes a calcium-binding G protein-coupled receptor (GPCR), with an extracellular N-terminal domain (containing the calcium binding sites), joined to the C-terminal domain via a seven transmembrane region (essential for its signaling function).

Bevacizumab is a recombinant VEGF antibody derived from a humanized mouse monoclonal antibody (93% human) that is composed of the mouse VEGF-binding site joined to a human IgG framework.

This platform comprises two elements, the coding sequence for the transcription factor AlcR (controlled by the CaMV 35S promoter), and the alcAmin 35S promoter, in which two AlcR binding sites are joined to the CaMV 35S minimal promoter [ 27].

These metal-binding functionalities are typically joined to a "ring" structure.

However, ZFNs and TALENs, which both comprise a nuclease joined to a site-specific DNA-binding domain, require the generation of a unique protein for each genomic manipulation (Wood et al. 2011).

When a modified PR-LBD is joined to specific DNA-binding and transcription activator domains, the resultant chimeric protein functions as an antiprogestin-inducible transcription factor for transgenes linked to promoters with specific DNA-binding sites.

An elementary task can be joined to a specific variable and its valuation or binding.

One method to reduce the presence of these information-poor binding sites is to apply stricter binding site conservation criteria.

Upon substrate binding, the two core domains join to form a 'closed state' containing an ATPase active site, while conserved DEAD-box protein motifs in D1 promote the unwinding of short duplexes bound to D2 by excluding one RNA strand and bending the other.

NCaBD containing two Ca2+ binding sites will need to be fit with a two binding site model.

Noteworthy, these binding sites are juxtaposed to GATA3-binding sites.