Sentence examples for binding sites is high from inspiring English sources

The in vivo affinity of GFP-MS2-nls for RNA containing MS2 binding sites is high (Kon/Koff = 500) [16].

The homology of the nucleotide sequences in the binding sites is high.

The degree of homology of the nucleotide sequences containing the miR-619-5p miR-619-5p miR-619-5pand miR-5096-3p binding sites is high.

The biological validation might offer one of the solutions for this predicament however if the number of predicted binding sites is high the experimental validation might not be feasible.

The absolute number of predicted binding sites is highest in exon 6a, which gives rise to the longest SHOX 3'UTR known to date, while the binding site density is highest in exon 6b.

A binding instance was defined if the matching score between its oligonucleotide sequence and the PSSM of the transcription factor binding sites is higher than a PSSM-specific cutoff, which was determined by the lowest matching score where the density of positively identified binding sites in the ChIP-enriched regions is 5 times more than the one in the background sequences (or FDR of ≤20%).

Additionally, the number of SNPs found in the predicted transcription factor binding sites is higher than in non-binding site sequences.

For each PWM family, we examined whether or not conservation within predicted binding sites is higher than that outside the sites (but still within the 200-bp promoter region) (see Methods).

It is important to emphasize that the high selectivity towards oligomers only can be obtained at a relevant time-scale, if the off-rate at each single binding site is high.

However, a postmortem study reported that the density of the D2R binding sites was higher in PD patients than normal controls [28].

Consistent with this, we found that the median enrichment level of Sty1 at the binding sites overlapped with the major Atf1/Pcr1 binding sites was higher than that of the Sty1 at the binding sites non-overlapped with the Atf1/Pcr1 binding sites (4-fold versus 2.3-fold higher than the array median; p-value = 3.03e-08) (Figure 6D).