These binding sites are called α-helical molecular recognition features, α-MoRFs, and have been well studied from protein complexes taken from PDB [ 105].
We do not include these data sets in CLIPdb because the mapping size would have significant impact on the binding sites being called.
ETS transcription factor bindings sites were called using MACS with a cutoff P value of 1e-05.
As seen in Fig. 3A, and detailed in Additional file 2: Table S2, 295 peaks denoting CgrA-binding sites were called as significant along the entire genome.
The site is called Is Winter Coming?
Those sites were called in both G1E and G1E-ER4 cells as occupant, yet their binding signals were significantly different.
Such sites were called "conserved sites".
A set of the same TF's conserved binding sites is always called a motif, which can be verified by experiments or predicted by comparing a set of DNA sequences potentially containing the TFBSs.
This kind of binding sites are also called a spaced dyad.
The site was called ProjectRunGay.
