Sentence examples for binding sites increased from from inspiring English sources

When Ishihara et al. also overexpressed the G-protein in COS cells transfected with secretin receptor, the number of agonists binding sites increased from 1.8% (of the total seen by the antagonist) to 15% (Ishihara et al. 1991).

As derived from our model, the flow of the binding (non-binding) species within the pore functionalized with binding sites increased (decreased) when related to that of the inert pore.

Interestingly, the number of SUMO-2/3 specific binding sites was increased by 12% (from ~27 k to ~57 k) while the number of SUMO-1 specific binding sites was decreased by 11% (from ~13 k to ~10 k) during viral reactivation.

During the differentiation of 3T3-L1 mouse pre-adipocytes the number of genomic binding sites for PPARγ increases from a few to more than 5,000 [4]; [5], which implicates that this nuclear receptor regulates hundreds of genes during adipogenesis.

Targets with multiple (prerequisite or allosteric) binding sites have an increasing importance in drug design.

Zhu et al. [ 59] showed that combining information from TF binding sites and PPI data increased overall predictive power.

Insulin treatment increased the number of alpha(2)M* high (alpha(2 MSR) and low (LRP/alpha(2 MR) affinity binding sites from 1, 600 and 67,000 to 2,900 and 115,200 sites per cell, respectively.

The repressors were expressed from linear templates carrying the J23151 promoter and the BCD7 ribosomal binding site with time-varying concentrations, which were increased from 0 to 2.5 nM and decreased back to 0 during the course of the experiment (Niederholtmeyer et al., 2013).

Interestingly, the WT-QR, which has mutations only in the NAD+ binding site, also exhibited increased specificity toward 3-HPA.

g, Motifs identified within BCL11A binding sites from BCL11A ChIP seq in HUDEP-2 cells.

(B) A conserved SigB binding sites were found from 29 TSSs (p-value of 1.51 × 10−8).