Your English writing platform
Discover LudwigSuggestions(1)
Exact(2)
Mapping of transcription factor binding sites in selected genes was performed using software from Genomatix Software Gmbh, Munich, Germany.
Among the several approaches taken by ENCODE to investigate the different aspects of transcript regulation, the mapping of chromatin modifications and transcription factor binding sites in selected human cell lines using ChIP-Seq [ 6, 7] is probably the most comprehensive.
Similar(58)
We used a conventional ChIP assay, followed by Quantitative real-time PCR (QPCR) with primers from the regions identified in the promoter arrays, to validate the c-Myb binding sites in these selected genes.
The analysis of results of amino acid binding sites in vitro selected RNA aptamers is thorough, and the Fibonacci process-inspired model for the evolution of tRNAs is truly insightful and thought-provoking.
Instead of looking at individual TF binding predictions that are prone to contain false positives, we used the Fisher's exact test to search for enrichment of binding sites, in comparison to randomly selected gene set.
Hence, we would expect to find Sp1 binding sites in many of the randomly selected negative examples.
In order to explore the functional importance of the selected binding sites in different contexts, we elaborate our previous model of gap gene expression hereinafter referred to as Model 1 [ 5].
The identified TFBS were visually inspected for 100% sequence conservation of the core sequence in human, mouse, rat, and dog, and 23 different putative Sox binding sites in 10 genes were finally selected for ChIP assay.
High confidence sites were defined by our ability to empirically validate selected PR binding sites in independent samples (Additional file 2).
A bioinformatic screen for RUNX1 binding sites in promoter regions of 27 genes selected for their strong expression in human granular and spinous keratinocytes revealed highly conserved RUNX1 binding sites (score>0.9) in the promoter sequences of 3 genes.
Zebrafish nebulin has very small introns which make selecting PTM binding sites in the mutated area challenging.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com