Your English writing platform
Discover LudwigSuggestions(5)
Exact(11)
Table 1: Promoters of genes contain Pax3 and FRα binding sites in close proximity to each other.
We conclude that it is unlikely that there exist two tropane binding sites in close proximity to one another on either the DAT or SERT.
Chromatin remodeling might then involve making only subtle alterations to a distinctive chromatin higher-order structure already possessing transcription factor binding sites in close proximity in three dimensional space.
In support of this possibility, there are HIF binding sites in close proximity with the XBP-1 "A" site occupied in response to ER stress (Figure 4B) in all three species.
The presence of multiple binding sites in close proximity significantly increases the probability of interactions between miRNAs and mRNAs, even if mutations occur.
Although C/EBP is also described to have binding sites in close proximity to NF-κB TFBS, promoter analysis did not reveal its significant overrepresentation.
Similar(48)
We found that the miR-181a/-2a* miR-181a/-2a* miR-181a/-2a*inding site in close precursor to its TSS (Table 3), suggesting its direcontainsation of theSOX2iRNAs.
However, we were able to enhance the discrimination of KOD exo- by increasing the steric crowding of the template binding site in close vicinity to the residues bearing the C or 5mC of interest.
In this regard, HDAC family member 8 appears to be an attractive target, as crystal structure analysis revealed a unique second metal binding site in close proximity to the main catalytic domain, which distinguishes this HDAC isozyme from the other classical deacetylases.
Consistent with this model, statistically significant placement enrichment of human-specific NANOG-binding sites in close proximity to the genomic coordinates of protein-coding genes regulating brain size that are rapidly evolving in primates, pluripotency lncRNAs, functional hESC enhancers, and EDEs was observed.
Some common transcriptional targets of both pathways have Smad and TCF/LEF-binding sites in close proximity, indicating that the two pathways have synergistic activity among their downstream effectors, including Emx2 (Theil et al., 2002), Msx2 (Willert et al., 2002; Hussein et al., 2003), c-myc (Hu and Rosenblum, 2005) and Xtwin (Labbe et al., 2000; Nishita et al., 2000; Letamendia et al., 2001).
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com