Sentence examples for binding sites found in from inspiring English sources

The prevailing dogma posits that most transcription factor binding sites found in silico – although they would readily bind the protein in vitro- will not have a functional role in vivo (a concept defined as the "futility theorem" [31]).

Related studies on mycoremediation have indicated that contaminant heavy metals can be biosorbed by mushroom bodies at binding sites found in the cellular structure [20].

Pax2 and Sox2 binding sites found in the pou3f4 HCNR 81675 were subjected to site-directed mutagenesis.

Electrophoretic mobility shift assays were performed to evaluate the binding of the NF-κB transcription factor to the hypothetical binding sites found in COQ7 gene.

263 of the 442 high confidence HSF binding sites found in that study coincided with HSF binding segments we found (Table S2).

This conservative estimate of the number of HSF binding sites found in introns still represents a 2-fold enrichment over the background distribution since only 17.1% of euchromatin is intronic.

Photoaffinity labeling with isoflurane and propofol photolabels identified a common binding site in the immediate proximity of the anesthetic binding site found in the crystal structure of the anesthetic-GLIC complex.

Finally, we show that genetic variants associated with risk of neurodegenerative diseases beyond frontotemporal lobar degeneration are enriched in CTCF-binding sites found in brain-relevant tissues, implicating CTCF-mediated gene regulation in risk of neurodegeneration more generally.

Chromatin immunoprecipitation (ChIP) using synchronized CRC-myc flowers at stage 6 followed by qPCR revealed a strongest association of CRC-myc with the YUC4-III DNA fragment, which contained three evolutionarily conserved YABBY-binding sites found in CRM4 (Fig. 3a, c).

To investigate the diversity and universality of ligand-binding sites in protein structures, we conducted the all-against-all atomic-level structural comparison of over 180,000 ligand-binding sites found in all the known structures in the Protein Data Bank by using a recently developed database search and alignment algorithm.

The three Sall2-binding sites found in the proximal promoter of the human NOXA gene display the same core sequence (GGGCGGG).