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In the present study, we first showed that there was no correlation between the in vivo antidiabetic activity and the in vitro affinities for the I1/I2 binding sites for several substituted aryl imidazolines.
The structure correlates well with the appearance of RSV-F in electron micrographs, and the residues identified as contributing to specific binding sites for several monoclonal antibodies are arranged in appropriate solvent-accessible clusters.
Many individual genes contained binding sites for several of the homeobox transcription factors (Table S6).
We find predicted binding sites for several key factors (Figure 6).
The PTGS2 promoter region contains binding sites for several key cis acting regulatory elements [39].
Sequence analysis revealed conserved binding sites for several miRNAs in the Mitf 3'UTR sequence.
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It has been reported that LDLC binds directly to platelet glycoprotein receptor which serves as the binding site for several agonists including fibrinogen, fibronectin, thrombospondin and vitronectin (Hantgan et al. 1990; Asch et al. 1990; Plow et al. 1985; Parise et al. 1986).
This pocket is also the reported binding site for several other small molecules, including BD3 and BM4 (Ref. 88).
A second pocket in the CANTD serves as the binding site for several other CA-based inhibitors, the best characterized being PF74 (also known as PF-3450074 89,90. PF-3450074 89,90
The tyrosine residue is located within a YVKM motif and this has been shown to serve as the binding site for several molecules (Fig. 1).
Ligand binding of integrins results in catalytic activation of FAK and in its autophosphorylation at tyrosine residue in position 397 (Y397), which serves as a binding site for several Src homology 2 (SH2) domain-containing proteins, including Src kinases [ 22].
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binding sites for nuclear
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