Sentence examples for binding sites for human from inspiring English sources
To analyze DEGs, we assembled a dictionary of binding sites for human TFs and unconventional DNA-binding proteins (uDBPs) [33].
DNA methylation presents distinct binding sites for human transcription factors.
Known binding sites for human TFs were parsed from several public databases in January 2006.
Some of the conserved ELMs, like the SH3 ligand sites on NEF, have been experimentally verified as binding sites for human proteins [ 28].
It is possible that the observations are an artifact and the identified putative transcription factor binding sites are not real binding sites for human genes.
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For example, the vast majority of experimentally defined binding sites for the human skeletal muscle-specific transcription factors are confined to the most constrained orthologous sequences in the rodent genome [11].
Interestingly, according to the predictions of the miRanda-mirSVR algorithm, miR-23a/b also have putative binding sites for the human caspase-3 gene.
There are 22 putative binding sites for the human E4BP4/ NFIL3, about 6-fold above statistical frequency, as shown in Figure 6A, with an additional one in exon 23 (not shown).
In silico analysis of this sequence variant by TESS (www.cbil.upenn.edu/cgi-bin/tess/tess) and by the Genomatix SNP Inspector (www.genomatix.de) revealed a gain of transcription factor binding sites for the human-specific allele ("T") in comparison to the non-human variant ("C"), for factors such as NEUROD1, Upstream stimulating factor ½, E-box factor, TAL-1, DEP2, c-Myc and NF-kappaE2.
