Sentence examples for binding sites for cellular from inspiring English sources

The activation of transcription by LANA is directed by many promoters containing binding sites for cellular proteins including ATF, AP-1, CAAT, or Sp1, which are linked to a TATA box [16].

To assess the effects of LCR variations on binding sites for cellular transcription factors, the TFSEARCH software was used [ 16].

Collagens form supramolecular assemblies with multiple binding sites for cellular receptors [18] and it is tempting to think that clustering by their multivalent ligands is what activates DDRs.

The promoter region contains several binding sites for cellular transcription factors such as TFIID (Dostatni et al, 1991), Sp1 and E2 (Tan et al, 1992), all of which modulate its function.

The U3 region of the LTR typically contains binding sites for cellular proteins that promote transcription initiation, and are capable of activating or enhancing the expression of nearby genes in a tissue-specific manner [ 30].

Data presented here show that CAP remains bound to HIV-1 after removal of unreacted compound, impairing virus infectivity due to blockade of binding sites for cellular coreceptors CXCR4 and CCR5.

The structure of synaptophysin suggests that the protein may function as a channel in the synaptic vesicle membrane, with the carboxyl terminus serving as a binding site for cellular factors.

It is predicted that the variation of A7515C in the C7294T co-variation can result in loss of a binding site for the human activator AP-1, while the variation of A7602G result in an addition of binding site for cellular transcription factor Oct-1. AP-1 is a Jun/Fos heterodimer complex protein that activates transcription of E6 and E7 genes.

26 As full-length vinculin contains binding sites for numerous cellular binding partners regulating focal adhesions, cell cell junctions, and cell motility, 35 force-activation of vinculin may result in subsequent vinculin dependent cellular signaling.

In addition, unpaired nucleotides can fold into complex three-dimensional topologies that create specific binding sites for other cellular RNAs, small molecules, and proteins that, when bound, can alter the underlying fold and regulatory function of the RNA [ 4].

Leaky expression of viral genes from replication-deficient viral vectors, however, is known to occur due to the presence of binding sites for certain cellular transcription factors in adenoviral promoters [ 43].