Sentence examples for binding sites encoded by from inspiring English sources

Another factor that complicates the lactose repressor literature is the complexity of the multiple binding sites encoded by the operator, which promote DNA looping and the mutual stabilization of dimers bound in cis to each other.

The majority of the important amino acid substitutions identified in this study as associated with survival to day 100 are located on the alpha 1 or the alpha 2 domains of the peptide binding site, encoded by exons 2 and 3 respectively and are predicted to directly affect T-cell allorecognition [ 21- 23].

The conservation of miRNA binding sites encoding oligopeptides has been revealed.

The additional ubiquitination sites of 0N4R and 2N4R tau in comparison to 2N3R tau allows us to assume, that these ubiquitination sites are localized in the second microtubule binding domain encoded by exon 10, which contains 5 lysine residues.

Tau isoforms with 0, 1, or 2 N-terminal inserts are generated by alternative splicing of exons 2 and 3. A schematic representation of tau isoforms, 3R2N and 4R2N, including the microtubule binding repeat domains encoded by exons 9 12, the N-terminal inserts encoded by exons 2 and 3, and the location of potential heparin binding sites, are shown in Figure 1A.

Other factors are also required, including one that appears to act through homeodomain protein binding sites and may be encoded by extradenticle (exd).

Addtionally, putative binding sites for GAGA factor encoded by the Trithorax-like gene (Trl) characteristic of TREs (Trithorax Response Elements) are found in −4.0 kb from the duf start site (Figure 1).

The number of microtubule-binding repeats is determined by the inclusion or exclusion of the second microtubule-binding repeat encoded by exon 10 of the TAU gene.

These GOFs contain several transcription factor binding sites identified by ENCODE ChIP-seq, including one ∼400 bp peak observed in brain cancer cell lines among other tissues and containing 7 human-specific substitutions in an alignment of great apes (see Methods).

In the SEREX-ovarian dataset, six TFs were detected with enriched binding site numbers, namely those encoded by GATA1, MYOD, NFKB, IK1, HIF1 and ARNT.

The NP-1-binding site in VEGF165 is encoded by VEGF exon 7, which is absent in the VEGF isoforms VEGF121 and VEGF145 (Soker et al, 1997).