Sentence examples for binding sites does not from inspiring English sources

According to Istvan et al.[17] the orientation of the side chains in the binding sites does not differ among the statins.

Deletion of these binding sites does not inhibit the function of Y RNAs during chromosomal DNA replication in vitro and in vivo [7], [10].

Our previous study showed that mutation of all four Sp1 binding sites does not impair the activity of this hTR core promoter or its ability to be transactivated by NF-Y, but disrupts Sp1 binding and activation [ 13].

However, many of these putative PhoP-binding sites are likely to be false positives because many sequences containing the putative binding sites did not bind PhoP when they were assayed by ITC (Table S1 of the Supporting Information).

Although CLIP approaches can identify non-canonical sites that bind the miRNA with some degree of specificity, these non-canonical binding sites do not function to mediate detectable repression.

Compared with SPR measurements, the non-specific binding caused by the polymer matrix and/or randomly located fluorescent monomer residues that did not compose specific binding sites did not contribute to the observed fluorescence change.

Interestingly, the MCIB RAD21 binding sites did not show a characteristic directional binding to the pluripotency transcription factor motifs as seen for CTCF co-bound sites.

This leads us to conclude that the occupation of PDE non-catalytic binding sites do not explain the increase of τD in low Ca2+.

Since the binding sites do not differ, the explanation for the higher affinities in OpuAC from L. lactis must lie elsewhere in the protein.

Mutation of one of the three SRY binding sites did not result in significant change in promoter activity, while mutation of two binding sites significantly decreased the activity of the Tcf21 promoter.

A TransFac search for commonly occurring transcription factor binding sites did not reveal any significant differences between the genes with altered transcript levels and a set of genes on the microarray which did not exhibit altered transcript levels (not shown).