Sentence examples for binding sites described by from inspiring English sources

Only six matches in the whole genome can be found for the conserved possible HMGA2 binding sites described by Cui and Leng [12] (NCBI refseq human genomic sequences build 36).

We have argued that our scoring function captures the essence of true cis-binding sites in a genome so that if the genome contains functional binding sites described by the profiles, its LOR(s) will become positive when the score value s increases beyond some threshold; and the larger a LOR(s) value is, the higher the confidence for the prediction is [ 13].

Genes that map within 1 kilobase (kb) of an ORC-binding locus were identified by in-house built Perl-based programs, which determined whether the starting or ending nucleotide coordinates for genes were found between 1 kb to the left and 1 kb to the right of the coordinates for DNA loci that contain potential ORC binding sites described by [ 18].

As implied by the binding sites described above, hPSC-vitronectin adhesion is mediated by αvβ3/β5 integrins and HSPGs [ 8, 42].

Many AML types are characterized by mutations in C/EBPα and RUNX1, which would impact many of the binding sites described here.

In contrast, the truncated plectin produced by c.13458_13473dup harbors the IF-binding site described above.

This model describes the regulation of the tryptophan concentration via different mechanisms, i.e. genetic regulation via binding of tryptophan to it's operator site, described by C x4 t1 mRNA mRNattenuationon (C x4 t2 m2)) and enzyme inhibition (C x4 t3 m 3)).

This binding site was described by the authors on the β-lg dimer interface, binding 2 mol of palmitate per dimer of β-lg with an affinity constant in the order of 10 M−10

This site matched the composition of the M1 moiety of the full CTCF binding site recently described by Schmidt et al. (2012).

A binding site is described by any amino acid for which at least one heavy atom is closer than 4.5 Å from any heavy atom of the bound pharmacological ligand.

The evolutionary correlation between ligand binding sites, ligand structure and protein function has also been demonstrated by a network of ligand-binding-site similarity described by Park & Kim [3].