Sentence examples for binding sites demonstrated that from inspiring English sources

Competitive binding using the site markers warfarin and ibuprofen, having definite binding sites, demonstrated that both forms of sanguinarine bind to site I (subdomain IIA) on BSA.

Easy removal of Pb II) ions from the binding sites demonstrated that the AMPS nanogels might be effectively reused several times made it economically suitable for use.

Global gene expression profiling combined with computational and experimental analysis of transcription factor binding sites demonstrated that p53, along with FOXO, MITF and USF1, contributed to gene induction in response to PI 3-kinase inhibition.

The correlation between gene expression levels with the detected MCF7 and PANC1 "Only" TCF7L2 binding sites demonstrated that QChIPat is also applicable to compare narrow peaks in two ChIP-seq samples such as TFs in addition to broad peaks such as repressive histone modifications.

As shown in Figure 3A, titration of scCPX into the unblocked SNAREΔ60 results in a thermal graph characteristic of a reaction involving multiple binding sites, demonstrating that CPX has more than one binding site per SNAREΔ60 complex.

Further enzymatic test aided by molecular docking simulation in the ATP-binding site demonstrated that 9a and 9b are potent inhibitors of c-Kit kinase.

Once RUNX1/ETO is depleted, C/EBPα expression levels increase and this factor then occupies a large number of binding sites, demonstrating at the genome-wide level that (1) C/EBPα is a major driver of myeloid differentiation and (2) the differentiation block in AML is partly caused by C/EBPα downregulation.

Binding studies with truncated SmDia clones identified SmTK3 interaction sites demonstrating that maximal binding efficiency depends on the N-terminal part of the FH1 (formin homology) domain and the inter-domain region of SmDia located upstream of FH1 in combination with the unique site and the SH3 domain of SmTK3, respectively.

Approximately 6%% of GR binding sites demonstrate a pattern of remodeling that can also be described as "phased", where the deltaK4methyls signal shows distinct, alternating peaks and valleys.

Wnt1 and β-catenin depletion and overexpression of nuclear β-catenin, together with TCF binding sites activation demonstrated that ABCB1 is positively regulated by the canonical pathway of Wnt signaling.

Here we have created a homology model of the RDL binding site and demonstrated that GABA and a range of GABA analogues can dock into this site with a range of potential interaction with binding site residues.