Sentence examples for binding sites comprising the from inspiring English sources
To examine possible functional implications of SNP rs2734647 in the 3′UTR on microRNA (miR -dependent regulation of gene expression, in silico analyses were performiR -dependentetScan (regulation2) (Lewis et al, 2005; Grimsof et al, 2007) and PITA (Kertesz et al, 2007), resultingene thexpressionon of 4 minsilico seed binding sites comprising the SNP rs2734647 position (i.e., c.*3638analyses
Within the 760 bp region upstream of Agrp defined by mouse/human sequence conservation, the IREs and STAT binding sites comprise the majority of non-coding sequence conserved among mammals.
The molecular interaction fields (MIF -based analysis of cavities coMIF -based MD findings indicanalysisputative binding site cofprising the same residues determining epitope reorganization.
It is well established that the NBDs of ABC transporters form a sandwich dimer with two composite ATP-binding sites comprising the Walker A, Walker B and H-loops of one NBD and the signature motif of the other [ 47]; Figures 1 and 3.
Interestingly, the majority of these same matrices were found enriched also in the ERβ binding sites comprising hEREs or EREs, suggesting that one or more such DNA matrices might cooperate with ERβ for either DNA binding or gene trans-regulation.
The selected amino acid binding sites, comprising 337 independently derived sequences (18,551 nucleotides in total) directed at eight amino acids, are described in [ 12].
In this way we could identify 1271 ERα-only and 4541 ERβ-only binding sites, comprised in these regions, none of which showed nearby binding of the other receptor.
PPP1R15B functions by association with PPP1C through a binding site comprising residues 513 713 (4); the familial variant is located within this critical domain.
RETECD envelopes the dimeric ligand complex through a composite binding site comprising four discrete contact sites.
Brandt and co-workers have suggested a "hydrophilic entrance" to the hydrophobic site, allowing hydrophilic quinones to bypass the inhibitor block (22), and Tormo and Estornell suggested a large quinone and inhibitor binding site comprising both hydrophobic and hydrophilic domains (23).
