Sentence examples for binding sites compared with from inspiring English sources
Furthermore, HCD122 is also a potent mediator of antibody-dependent cellular cytotoxicity (ADCC), lysing B-CLL cells more efficiently than rituximab in vitro, despite a significantly higher number of cell surface CD20 binding sites compared with CD40.
Finally, bioinformatic analyses displayed that amphioxus ASPP protein could interact with REL protein by conserved binding sites compared with human ASPP2 protein, which seemed to further suggest that the amphioxus ASPP protein involve in innate immunity through NF-кB signaling pathway.
We identified the human homologue of the MyHC-EO gene in GenBank, and analyzed the 5; upstream region, which revealed a paucity of muscle-specific transcription factor binding sites compared with the other MyHC genes.
Lovo li had significantly less FdUMP binding sites compared with Lovo 92, Lovo B2 and Lovo 175X2 cells.
Applications on three human TF ChIP-seq datasets demonstrate the advantage of SeqSite for its higher resolution in pinpointing binding sites compared with existing methods.
In the larvae, dE2F2 was found to have nearly 4000 binding sites, compared with dE2F1, which only has less than 300 binding sites (Korenjak et al. 2012).
This may account, at least in part, for the reduced tumour growth in vivo observed for cells expressing β6 that lacks the ERK2 binding site compared with cells expressing wild-type β6 (Ahmed et al, 2002).
Luciferase activity was significantly decreased in cells transfected with the PCAF 3'UTR construct with the potential binding site, compared with cells transfected with the empty control vector or the mutant 3'UTR mutant (ACTTT to AGAAT at the putative binding site), suggesting endogenous translational repression of the construct with the PCAF 3'UTR.
However, in contrast to residues on the left of the groove in Figure 4, residues Ile173 and Ala179 in human mincle are shifted away from the binding site compared with the corresponding residues in bovine mincle, which form the right side of the groove.
As illustrated in Figure 3, the crystal structure shows erlotinib (green in Figure 3A) to be slightly shifted in the binding site compared with its predicted position in the model (yellow in Figure 3A); to the left in the aspect of the Figure by approximately 1 Å.
Furthermore, CaM binding to Nav1 C termini lowered Ca2+ binding affinity and cooperativity among the CaM-binding sites compared with CaM alone.
