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If nuclear localization signals and nucleic acid binding sites can comprise cationic patches sufficient to bind GAGs, antibodies directed against such patches would be potentially auto-reactive and therefore strongly selected against.
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These binding sites can be considered as prerequisite or allosteric binding sites.
Some fluorescent probes have specific binding to different regions of the HSA, and the binding sites can be determined by the displacement binding experiments using some probes.
In addition, the electrostatic potential binding energy and similarity between the binding sites can be calculated based on the binding pose of the ligand.
Substantial similarity of EA receptors regarding their binding sites can be assumed.
However, the sequences of binding sites can be very heterogeneous.
The value of n of BSA at all three studied temperatures is approximately equivalent to 1 as fractional binding sites don't occur and no < 1 binding site can be present suggesting only one binding site for rivaroxaban.
The surface proton binding site can be determined by acid-base titration method.
Each hormone binding site can be divided into an inner and outer binding cavity.
In addition, an individual domain or binding site can mediate binding to more than one protein.
Other than SNPs within miRNA target sites, SNPs outside miRNA binding site can affect miRNA function.
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