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Classical and non-classical binding sites can coexist in the same cells [ 1, 2].
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Each viral genome contains multiple polymorphisms across the genome, and within an individual a polymorphism at one site can coexist as a mixed population with the corresponding consensus at that site.
Individual binding sites can be observed via the green FitCons2 class 40 (ρ = 0.43).
These binding sites can be considered as prerequisite or allosteric binding sites.
Two RAP1 binding sites can substitute for the wild-type initiation site.
This suggests that these alternative binding modes can coexist with the high-affinity mode at protein concentrations lower than those needed to fully populate them.
This suggests that Sgt1 interacts primarily with the N-terminal lobe of Skp1 and can coexist in Skp1 complexes with Skp2 (and probably other F-box proteins), the binding site of which is in the C-terminal lobe.
They can coexist.
"But both can coexist.
These businesses can coexist".
We can coexist".
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