Sentence examples for binding sites between the from inspiring English sources

First, QAs and other related drugs bind at potassium binding sites between the selectivity filter and the gate and are further stabilized through favorable hydrophobic interactions with the cavity wall.

The computer docking simulation was then performed to determine the most plausible binding sites between the model structure and target gases, trimethylamine, ammonia, acetic acid, and o-xylene.

In fact, their multivalent character allows the creation of multiple binding sites between the positively charged groups that decorate the surface of cationic dendrons and dendrimers and the negatively charged phosphate groups present on the strands of siRNA and DNA.

The NMR structures and Autodock analysis suggest that the pocket with the most favorable amphipathic property for anesthetic binding is located between the W15 side chains at the center of the dimeric hydrophobic core, with the possibility of two additional minor binding sites between the F12 and F52 ring stacks of each monomer.

It can also achieve more precise localization of binding sites between the RNA and protein [ 58].

Furthermore, additional binding sites between the TBC[4] fragments in each L1 are occupied by MnII ions.

MatInspector [14] detected a remarkable difference in the number of potential transcriptional regulatory binding sites between these haplotypes: ten for the former haplotype, while only two for the latter haplotype (Figure 3).

The first K+ ion became initially bound at about 1 ns and reached quickly to the upper binding site between the top and central G-tetrads.

The GABA binding site is located at the interface between α and β subunits while flumazenil and other benzodiazepines act as positive allosteric modulators on a distinct binding site between the α and γ subunits.

While the second K+ ion reached the lower binding site between the bottom and central G-tetrads through the bottom pathway, it bound at 159.3 ns and spent about 5.6 ns to accomplish the binding process.

GABA, the endogenous agonist of GABAA receptors, binds at an orthosteric site located at the interface between α and β subunits (Fig. 1a) [5, 6] while benzodiazepines (including isoflurane), a clinically important class of sedatives and anxiolytics, act as positive allosteric modulators by interacting with a distinct binding site between the α and γ subunits [4, 6].