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Two of them, the lid and β9 loop, expose a large hydrophobic surface and are considered as acyl chain binding sites based on their interaction with an alkyl phosphonate inhibitor.
We identified binding sites based on 584 positional weight matrices (PWM) for vertebrate transcription factors in TRANFAC v10.2[14].
The enhanced precision in the large-scale mapping of binding sites occupied in vivo might also overcome some of the limitations of descriptors of binding sites based on conventional ChIP-chip approaches.
In recent years, many computational methods such as regression based approaches have been proposed to discover transcription factor binding sites based on gene expression data.
Although this region shows weaker conservation across species, it contains a single HRE half-site, similar to those in Region I, and four potential cone-rod-homeobox (CRX) transcription factor binding sites based on previously identified consensus sequences [ 71, 72].
The edges of this tree are then, in the 6th step, annotated with all gains and losses of transcription factor binding sites based on the node annotations generated in the step before.
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The pathway for monomethylcurcumin is defined around binding site based on calculation.
In addition, this variant is predicted to disrupt a transcription factor binding site based on our analysis (Conde et al. 2006).
Herein, is an account of synthesis and characterization of reasonably designed turn-on fluorescent probe SGPB1 with Salicylhydrazide as binding site based on BODIPY adapted fluorophore.
The Flpp3 structure demonstrates a globular protein with an electrostatically polarized surface containing an internal cavity a putative binding site based on the structurally homologous Bet v1 protein family of allergens.
OBJECTIVE Clinical genetic testing is commercially available for rs61764370, an inherited variant residing in a KRAS 3' UTR microRNA binding site, based on suggested associations with increased ovarian and breast cancer risk as well as with survival time.
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