p53 is a transcriptional activator that binds to sequence-specific binding sites at the promoters of several cellular genes and activates their transcription.
It is conceivable that TRiC might bind fibrils through one of its ends while the binding sites at the other end remain available to snatch mhttQ51 oligomers lurking in their proximity.
A ribosome has two tRNA binding sites; at the first site, one tRNA attaches to the amino acid chain, and at the second site, another tRNA carrying the next amino acid is attached.
We showed that Lbpro possesses specific binding sites at the non prime side from S1 down to S7 [Santos et al. (2009) Biochemistry, 48, 7948 7958].
To explore the possible binding sites at the interface of tripanosomal triosephosphate isomerase, fully flexible benzothiazoles were docked onto the dimer interface.
Ketamine is a dissociative anesthetic that acts on glutamate binding sites at the N-methyl-D-aspartate (NMDA) receptor as well as at opioid, monoaminergic, cholinergic, nicotinic, and muscarinic receptors [18].
It has previously been shown [24] that both Al and Fe can compete with Cu for binding sites at the DOC, especially in cases with low Cu levels, affecting the speciation in the water.
For the multiple binding sites system, Zhang et al. proposed a multiple binding sites equation that could calculate the binding constant and the number of binding sites at the same time [127].
where T is the temperature, k B is the Boltzmann constant, is the energy barrier to diffusion, and i and j are the labels of the binding sites at the beginning and end of an adatom's hop.
The mode of inhibition was deduced to be non-competitive with the chloride interacting with precursor binding sites at the electrode surface, since increased [H2O2] did not decrease the degree of inhibition.
Controlled electropolymerisation of dopamine around the complex served to both entrap the complex, holding the aptamer in, or near to, it's binding conformation, and to localise the PSA binding sites at the sensor surface.
