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Micro- and nanostructured imprinted materials possess regular shapes and sizes and a small dimension with extremely high surface-to-volume ratio with binding sites at close proximity to the surface [4].
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It has been reported that the two close GABP binding sites at gene ITGB2 are both essential for transcriptional activation [ 39- 41].
Second, the evolutionary spacing across the sensu stricto species between the Rap1 and Abf1 binding sites at HMR-E is known, but how close the ACS has to be to either of those sites is unknown (Teytelman et al. 2008).
The rice transposon Osmar14 has a secondary transposase binding site close to one of the two principal binding sites at the transposon ends (Yang et al., 2009).
This comparison for LRH-1 binding sites at the Pemt and Aifm2 loci is shown in Figure 7B and clearly shows the close apposition of the binding peaks for the two different ChIP-seq data sets.
Experiments show that it performs better than or similarly with existing methods on the accuracy of binding site detection, but SeqSite can locate binding sites at a higher resolution and can pinpoint adjacent binding sites even if they are as close as 40-bp from each other.
Close to each nonannular binding site at the monomer monomer interfaces in KcsA are two Arg residues, Arg-64 and Arg-89.
Alternatively, Lis1 might regulate the linker domain's motions, as the distal end of the linker lies in close proximity to the Lis1 binding site at AAA3/4.
a, 2mFo−DFc electron density map (blue mesh) of residues around the methylguanidinium binding site at 1σ. b, Overlay of guanidinium binding site (green) and methylguanidinium binding site (orange).
(b) The substrate binding site at the subunit interface of apo-MccB.
Intercalating agent action depends on molecules chemistry and on the binding site at the double helix.
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