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Their potential binding sites, as indicated by the iCLIP data, are shown in Fig. 4C.
A strong interaction with particular activated receptors is mediated via the Grb2 binding sites, as indicated by various lines of evidence.
(B – B′ ) Band shift experiments between Nv HoxB or Nv HoxE and Nv Pbx on the three different classes of binding sites, as indicated.
The CLR01 interaction was very similar among all the different lysine and arginine binding sites as indicated by similar (X-P) distances between the lysine ammonium or arginine guanidinium groups (X) and the bound phosphate group (P) in CLR01.
Band shift experiments are performed with mouse Pbx (Mm P) and Meis (Mm M) proteins on central (Meis-II ) and posterior (Meis-III ) Hox/PBC/Meis binding sites as indicated.
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C. metallidurans CH34, however, lacks a SoxS homolog and does not carry any typical SoxR binding site, as indicated by a genome-scale pattern search using the SoxR binding site consensus sequence [209] and the Regulatory Sequence Analysis Tools webservice (RSAT) [210] (results not shown).
Apart from the primary site, our goal was to find other, prerequisite binding sites, as well.
Regions in one of the states are significantly enriched with active genes and transcription factor binding sites (indicated as "plus states"), whereas regions in the other state are relatively less active (indicated as "minus states").
Recent studies on functional transcription factor binding sites have indicated, as expected, that a major telltale of functionality is a high degree of evolutionary conservation (Stone and Wray 2001; Vallania et al. 2009; Wang et al. 2012; Whitfield et al. 2012).
Upon ligand-binding, PR is globally phosphorylated at multiple sites, as indicated by a slight gel upshift [ 42].
The effects of each strategy upon the process of transcription and presence of underlying DNA elements such as transcription factor binding sites are indicated.
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binding partners as indicated
binding sites as reflected
binding sites as expected
binding sites as determined
binding sites as compared
binding sites as predicted
binding patterns as indicated
binding affinities as indicated
binding rates as indicated
binding sites as detailed
binding sites as seen
binding sites as shown
binding sites as described
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