Your English writing platform
Free sign upSuggestions(2)
Exact(2)
Therefore, lower uptake at pH 5.5 could be explained by an increased competition between protons and free metal ions for the same binding sites, as expected based on the Biotic Ligand Model [10].
Only expressed alleles exhibited an excess of nonsynonymous substitutions and codons under positive selection in the putative Antigen Binding Sites, as expected for functional MHC sequences [ 2, 6].
Similar(58)
Inhibition of RoDH4 by fluoxetine in the present study gave a best fit to a biphasic curve suggesting multiple drug binding sites, as might be expected for this multimeric protein (see Liden and Eriksson, 2006; Penning, 2011).
The imine linkages are expected to be responsible for providing binding site as well as fluorescent signaling sub-unit.
In another test we show that our predicted autoregulatory binding sites cluster surprisingly close to the transcription start sites as expected for functional binding sites but not for falsely predicted ones.
Although gaps are not expected in alignments of functional binding sites, we allow for them so that we can apply the same metrics to binding sites as the surrounding sequences.
It should be noted that the false positive rate of 9.2% for the predicted miRNA target sites could weaken but not bias our results, because the selection pressure on the falsely predicted miRNA binding sites is expected to be same as that on their flanking regions Population genetics is a useful tool to detect the evolutionary selection on miRNA target loci [ 13].
This gives indications of the robustness of the methods, as the biologically relevant binding sites are expected to be detected in each replicate.
Structural independence of binding sites is expected, in particular, for proteins with multiple binding sites located on different protein domains.
Recent studies on functional transcription factor binding sites have indicated, as expected, that a major telltale of functionality is a high degree of evolutionary conservation (Stone and Wray 2001; Vallania et al. 2009; Wang et al. 2012; Whitfield et al. 2012).
In contrast, as E2F1 is targeted to transcription start sites, between 80.4% to 85.8% of E2F1 binding sites would be expected to be identified on a promoter array.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com