Sentence examples for binding sites as defined from inspiring English sources

The promoter regions (2000bp upstream to the transcription start site) of the up, down and no-change sets were retrieved using BioMart and used to search for transcription factor binding sites as defined in the JASPAR CORE database [37].

Promoters from the input gene list were analyzed for enriched presence of 615 different known transcription factor binding sites (as defined in the TRANSFAC version 7.4 database).

We show that the activity of p63 binding sites as defined by co-localized H3K27ac signals, rather than p63 binding itself, correlates with the expression of nearby genes.

We show that the activity of p63 binding sites as defined by co-localization of histone modification mark H3K27ac signals correlates with the expression of nearby genes.

Indeed, the ΔNp63 proximal promoter harbors several potential Ets1 binding sites as defined by the presence of the core Ets binding motif GGAA/T (Fig. 6A).

Over 70% of hypermethylated DMRs and 35% of hypomethylated DMRs were located in open chromatin regions and transcription factor binding sites, as defined by ENCODE [ 35] (Additional file 2: Figure S2A).

For example, a common belief was that a specific transcription factor could bind to a few dozen genes whose core promoters contain its consensus binding site as defined in vitro, and once recruited to a promoter could almost single-handedly regulate transcription [ 13].

Annotated resonances correspond to the SH3 binding site, as defined in the sequence in Fig.  2e.

TFT 3.0 contains sets of genes that share a common predicted TF binding site as defined in TRANSFAC version 7.4.

Furthermore, inspection of the protein surface did not reveal specific CL-binding sites as defined by Palsdottir and Hunte (2004).

There was significant over-representation of KLF-A TFBS within the first 2 kb of promoter sequences from the stem list gene list (p value of < 0.01), as well as over-representation of octamer sites and extended Oct4-binding sites as defined from ChIP-PET data [ 60].