Sentence examples for binding sites as a from inspiring English sources

Gcn4p is a basic leucine zipper protein which interacts with DNA binding sites as a dimer [ 32], and is known to preferentially bind to several sequence motifs, including a 7-mer motif, TGACTCA [ 33, 34].

Descriptive statistical analyses based on the complete dataset including the comparison of bond angles and lengths as well as the description of torsion angles are performed to characterise the binding sites as a whole.

A variety of computational methods have attempted to exploit the evolutionary stability of functional regions by identifying ligand binding sites as a method to predict function [4], [5].

Inside the semipermeable bags of resealed red cell membranes the ligand leaves its protein binding sites as a monomer and appears in the water phase as such.

However, the size of the nucleosomes is significantly bigger than transcription factor binding sites, as a consequence the resulting configurations of nucleosomes can be more complex.

Receptor alkylation experiments have been used previously to reduce the number of binding sites as a way to obtain concentration response relationships with different τ values, but with common values for KE, Emax and KA.

The 3'-UTR of mRNAs generally encode multiple miRNA binding sites as well as binding sites for a variety of RNA binding proteins.

Integrative analyses of binding sites as well as splicing profile suggested a mechanistic model underlying RBM10-mediated splicing regulation, which could be subsequently validated by minigene experiments.

For example, taking the case of two adjacent binding sites as an example, many existing methods tend to identify a single site around the two binding sites' center, or report one region covering both sites [ 26], leaving binding site detection for a secondary step of sequence motif analysis.

PPT1 is structurally similar to lipases and has a peptide binding site as well as a well-defined fatty acid binding pocket.

We next generated heterologous Bim promoter-luciferase reporter constructs containing intact AP-1 and Runx-binding sites, as well as a mutated AP-1 or Runx-binding site.