Sentence examples for binding sites are likely from inspiring English sources

The majority of these binding sites are likely to represent bona fide regulatory sites.

Like human L1 elements, the CpG islands and potentially the transcription factor YY1 binding sites are likely to be required for transcriptional initiation of mouse L1 elements.

Gene transcript levels are directly derived from microarray data, while microRNA regulatory effects are modeled using mRNA sequence information, with the assumption that mRNA with similar putative microRNA binding sites are likely to experience similar posttranscriptional regulation.

Using the HapMap and Perlegen polymorphism data that map to a stringent set of putative binding sites in human proximal promoters, we apply the Derived Allele Frequency distribution test of neutrality to provide evidence that many human-specific and primate-specific binding sites are likely evolving under positive selection.

When in a protein complex, subunits with DNA or histone binding sites are likely to increase processivity by increasing the translocation velocity or lowering dissociation constants, as exemplified by the large DNA footprint and the putative encapsulation of the nucleosome in the central cavity of the RSC complex.

On the other hand, the receptor binding sites are likely to resist changes [ 48].

However, recent data have implicated that σ2 binding sites is likely to be the progesterone receptor membrane component 1 (PMRMC1) or within PMRMC1 complex which shares homology with cytochrome b 5, a heme-binding protein that activates cytochrome P450 proteins [18].

In light of the significance of this loop domain for binding MLL, this long-range dynamic coupling between the two binding sites is likely of functional significance.

The specificity of these similar binding sites is likely to be achieved through the competition among homologous TFs for the same binding site, which is governed by their thermodynamic equilibrium [ 48].

Consistent with these expectations, our results demonstrate that the G-quadruplex formed by the Sp1 binding sites is likely a structural element contributing to the increased recombination rate in U3.

Deviation in amino acid composition between AChBP and nicotinic receptors, particularly in the complementary face of the binding site, are likely causes for the observed SAR differences.