Sentence examples for binding sites are known from inspiring English sources

One concern is that computational searches for transcription factor binding sites are known to have a high rate of false positives [30].

Target genes bearing these binding sites are known to be important for various cellular processes, such as stress response, cell growth and development, and mitochondrial gene expression.

To start with, CTCF binding sites are known to be flanked by an array of phased nucleosomes.

KstR binding sites are known to be highly conserved across the Mycobacteria, out to Rhodococcus and Nocardia [ 36].

We here presented a novel approach to identify putative target genes for transcription factors where the binding sites are known.

In the first example we assume that all true binding sites are known, and therefore there is no need for using SPF.

However, the use of the DNA duplex stability data is limited because little verified information about TF binding specificities can be found from the literature and, therefore, binding specificities need to be learned from the data as well which currently requires that a set of verified binding sites is known.

Since SCPD is far from an exhaustive database, false positives cannot be counted, but these "precision" curves are hopefully reflective of the true precision if all true binding sites were known.

The spacing between translation starts and ribosome binding sites is known to affect translation efficiency [ 58].

Altered methylation of CTCF binding sites is known for some imprinted genes, e.g., H19, where one of seven CTCF binding sites shows parent-of-origin specific methylation.

Third, within the 300-nucleotide sequence upstream of the protein-coding region, individual TF binding sites were predicted by the maximum PWM score above the threshold because about 95% of TF binding sites were known to exist in these regions.