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Carbohydrate binding sites are considered important for cellular recognition and adhesion and are important targets for drug design.
In order to explain the different activities between the AChE and BuChE, the ligand binding sites are considered in both enzymes, such as active site and peripheral anionic site (PAS).
When only putative recombinase binding sites are considered, FL-CS-2798 and FL-CS8-2798 difrom from FL-2798 by five and eight nucleotides, respectively.
Two binding sites are considered to be homologous if they essentially overlap and if they are bound by homologous transcription factors based on HomoloGene [ 42]. "Essentially overlapping" means that the beginning or the ending of the two aligned predictions overlap.
Similar(56)
In this case, to make a fair comparison, only the residues located up to 5 Å from the ligands (i.e. those lining the BEN/ATP/PLP binding sites) were considered.
Two binding sites were considered distinct if their seed region loci in the multiply aligned 3'UTR sequences were different.
Based on this and the Virtual Cell simulations with a mobile genome, a second model with two discrete binding sites was considered.
The analysis was performed for all vertebrate transcription factor matrices in the 2009.1 release of TRANSFAC [50], and putative binding sites were considered to be evolutionarily conserved if matches were also found at the aligned positions in both chicken and frog sequences and had no gaps present in the multiple alignment of these species.
Top 7000 binding sites were considered in each condition.
Divergence of transcription factor binding sites is considered to be an important source of regulatory evolution.
SMAP was run specifying that only ligand binding sites be considered.
More suggestions(15)
binding sites were considered
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binding sites are not
binding sites are occupied
binding sites are shown
binding sites are observed
binding sites are overrepresented
binding sites are associated
binding sites are indicated
binding sites are required
binding sites are very
binding sites are enriched
binding sites are species
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